| Name: | Desmopressin |
|---|---|
| Item Code: | HV002 |
| CAS Number: | 62288-83-9 |
| Other name: | Desmopressin |
| Molecular formula: | C46H64N14O12S2 |
| Molecular mass: | 1069.23 |
| Sequence: | 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 acetate salt (Disulfide bond) |
| Purity: | ＞98% |
| Main usage: | Nocturnal enuresis,Central diabetes insipidus, polyuria, polydipsia, Mild and moderate forms of hemophilia A and von Willebrand disease |
Desmopressin (DDAVP) is a synthetic analog of vasopressin with low vasopressor activity. Apart from its increasing effect on water resorption by the kidneys, desmopressin raises plasma levels of von Willebrand factor and factor VIII.
In veterinary medicine, desmopressin is applied in the treatment of canine and feline diabetes insipidus.
【Test】 | 【Specifications】 |
Appearance | White powder |
Identification By HPLC | Retention time is same with the reference substance |
Molecular Ion Mass | 1189.32±1 |
pH Value | 4.0~6.0 |
Specific Optical Rotation | -72~-82 º (c=1%，HAc) |
Amino Acid Composition | ±10% |
Purity (HPLC) : | NLT 98.5 % |
Related Substances(HPLC) | Single impurity: <1.0% |
Acetic acid (HPLC) | 3.0~8.0 % |
Water Content(Karl Fischer) : | ≦6.0% |
Peptide Content : | NLT 80% |
Residual Solvents(Acetonitrile) | ≦0.05% |
Bacterial Endotoxins : | ≦500IU/mg |
Assay(By Anhydrous,Acetic Acid-free) | 95.0～105.0％ |
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