Name: | Eptifibatide |
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Item Code: | HG015 |
CAS Number: | 148031-34-9 |
Other name: | Eptifibatide |
Molecular formula: | C35H49N11O9S2 |
Molecular mass: | 831.97 |
Sequence: | 3-Mercaptopropionyl-Homoarg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bond) |
Purity: | >98% |
Main usage: | Non-urgent percutaneous coronary intervention, Unstable angina or non-Q-wave myocardial infarction |
Product Description
Eptifibatide is an inhibitor of platelet aggregation belonging to the class of RGD (arginine-glycine-aspartate) mimetics.
Eptifibatide reversibly inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor and other adhesive ligands to the glycoprotein (GP) IIb/IIIa receptors.
【Test】 | 【Specifications】 |
Appearance | White powder |
Solubility | Very soluble in water (>1mg/ml) |
Identification By HPLC | Retention time is same with the reference substance |
Molecular Ion Mass | 931.96±1 |
Specific Optical Rotation | -75~-95 º (c=1%,HAc) |
Amino Acid Composition | ±20% |
Purity (HPLC) : | NLT 98.0 % |
Related Substances(HPLC) | Total impurities <2.0% Single impurity: <1.0% |
Acetic acid (HPLC) | ≦12.0 % |
Water Content(Karl Fischer) : | ≦6.0% |
Peptide Content : | NLT 80% |
Residual Solvents(Acetonitrile) | ≦0.05% |
Bacterial Endotoxins : | ≦5EU/mg |
Assay(By Anhydrous,Acetic Acid-free) | 95.0~105.0% |